C24-propyl sterols and derivatives
Sigma Aldrich Fine Chemicals Biosciences Stigmasterol ~95% | 83-48-7 | MFCD00003630 | 10G
Stigmasterol ~95% | Purity: ~95% | Mol Wt: 412.69 | 83-48-7 | MFCD00003630 | 10G
Indofine Chemical STIGMASTEROL, Lipid Research, 83-48-7, 98+%, 1 gm
STIGMASTEROL, Lipid Research, 83-48-7, 98+%, 1 gm
Medchemexpress LLC HY-N0131 100mg Medchemexpress, Stigmasterol CAS:83-48-7 Purity:>98%
Medchemexpress, HY-N0131 100mg Stigmasterol CAS:83-48-7 Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Sertraline hydrochloride | 79559-97-0 | >99.9% | 342.69 | 10 MG
Sertraline hydrochloride is an antidepressant classified as a selective serotonin reuptake inhibitor (SSRI). It is researched for various conditions such as major depressive disorder and obsessive-compulsive disorder.
- Functions as a selective serotonin reuptake inhibitor (SSRI) antidepressant.
- Researched for major depressive disorder and obsessive-compulsive disorder.
- Inhibits high mobility group box 1 (HMGB1)- or tumor necrosis factor-α (TNF-α)-induced microglial activation.
- Produces optimal anti-depression effects in chronic unpredictable mild stress (CUMS)-exposed mice.
- Significantly reduces immobility time during forced swim test in female animals.
- Does not alter spontaneous locomotor activity in all three genotypes regardless of sex difference.
Medchemexpress LLC Stigmasta-5,22-dien-3-ol, (3β,22E)- | 83-48-7 | 98.5% | 412.69 | 1 G
Stigmasterol is an orally active, immunomodulatory agent with anti-inflammatory and neuroprotective effects. It can cross the blood-brain barrier. It activates AMPK, inhibiting NF-κB and NLRP3 signaling pathways. Stigmasterol reduces microglia-mediated neuroinflammation and alleviates cognitive impairment and Alzheimer's disease. It also regulates M1/M2 polarization of microglia through the TLR4/NF-κB pathway, reducing neuropathic pain.
- Orally active immunomodulatory agent
- Exhibits anti-inflammatory effects
- Neuroprotective properties
- Crosses the blood-brain barrier
- Activates AMPK
- Inhibits NF-κB and NLRP3 signaling pathways
- Reduces microglia-mediated neuroinflammation
- Alleviates cognitive impairment and Alzheimer's disease
- Regulates M1/M2 polarization of microglia
- Reduces neuropathic pain
Apexbio Technology LLC Sertraline HCl 79559-97-0 10mM (in 1mL DMSO)
Sertraline hydrochloride (CAS 79559-97-0) is a small molecule classified as a selective serotonin reuptake inhibitor (SSRI) It acts by inhibiting the reabsorption of serotonin (5-HT) into presynaptic neurons thereby increasing synaptic serotonin levels This modulation of serotonergic neurotransmission is widely utilized in neuropharmacological research to investigate the molecular and behavioral effects of altered serotonin signaling Sertraline HCl serves as a reference compound in studies of antidepressant mechanisms neurochemical pathway analysis and the modeling of affective disorders in preclinical systems
Sigma Aldrich Fine Chemicals Biosciences beta-Sitosterol from soybean, >=96% | 83-46-5 | MFCD00003631 | 1MG
beta-Sitosterol from soybean, >=96% | Purity: >=96% | Mol Wt: 414.71 | 83-46-5 | MFCD00003631 | 1MG
Sigma Aldrich Fine Chemicals Biosciences β-Sitosterol | 83-46-5 | MFCD00003631 | 25mg
β-Sitosterol | Purity: ≥95% | MW:414.71 | 83-46-5 | MFCD00003631 | 25mg
Sigma Aldrich Fine Chemicals Biosciences Stigmasterol | 83-48-7 | MFCD00003630 | 5g
Stigmasterol | Purity: 95% | Mol Wt: 412.69 | 83-48-7 | MFCD00003630 | 5g